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The steady-state 24-hour urinary glucose excretion in patients with type 2 diabetes mellitus and mild, moderate, and severe renal impairment was 42%, 80%, and 90% lower, respectively, than in patients with type 2 diabetes mellitus with normal renal function

Jardiance primarily works through the kidneys, but it is not generally considered harmful to them when prescribed appropriately

In regard to primary outcomes, l-carnitine supplementation significantly reduced ALT ( P -value: 0.003), AST ( P -value: 0.020), total bilirubin ( P -value: 0.026), and lactate ( P -value: 0.013) and significantly increased Alb ( P -value: 0.000) and total protein ( P -value: 0.001) in the intervention group, at the end of the study, compared with baseline

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