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In CHB infection, NK cells exhibit a dual role: they continue to suppress viral replication through non-cytolytic mechanisms, yet their heightened cytotoxicity contributes to inflammation, fibrosis, and progressive liver damage (75, 76)

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Funding Open Access funding provided by National Institute for Health and Welfare (THL)

This review is triggered when the member receives opioid prescriptions from three or more prescribers and the cumulative opioid daily dose is greater than or equal to 90 Morphine Milligram Equivalents (MME)