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Additionally, the exposed group demonstrated significantly higher PLA 2 and SMase enzyme activity, with their median values being 518 and 706 AFU/mg, compared to 267 and 444 AFU/mg in the unexposed workers

Furthermore, the anti-apoptotic and cyto-protective effects of melatonin could stabilize mitochondrial membrane and help reset m -Dys 663

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Future research should integrate multi-omics strategies, longitudinal human cohorts, and mechanistic models to clarify the role of the MGBA in neurodegeneration