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GLP-1s are extremely safe, easy to initiate, easy to self-dose, work across substances, are combinable with all existing SUD medications, and help people lose weight (which is highly motivating for adherence to treatment)
If you struggle to get enough protein through whole foods, consider adding a protein shake to your routine
Furthermore, since such medications help patients lose weight quickly, there is an increased risk of health problems if the body does not have enough time to adapt to the change in its physiology, hence caution must be taken when using any rapid weight loss medication option available today
Most people find this the most motivating phase because the results are obvious and the side effects are behind them
The enzyme aldose reductase which produces intermediate sorbitol is a NADPH requiring enzyme with a high Km for glucose [7], thus elevated intracellular glucose concentrations and an adequate supply of NADPH leads to a significant increase in the amount of sorbitol
