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Yet decades later, researchers still do not have a clear understanding of how DSIP may work, whether it has a meaningful physiological role in humans, or whether the early findings represent a reproducible biological effect

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This leads to better glycemic control and a lower risk of diabetes-related complications

Tirzepatide commonly causes fatigue , joint discomfort , and gastrointestinal effects like constipation as normal therapeutic side effects, especially during dose titration

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