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El beneficio glucmico parece llegar a un techo a partir de dosis ptimas, especialmente porque la mayora de los participantes ya tenan un HbA1c basal 8,5%, mientras que la prdida de peso contina aumentando con la dosis

Routine liver enzyme monitoring is not mandated for all patients

Incorporating foods rich in vitamin E, such as nuts, seeds, and green leafy vegetables, can help in managing stress and keeping cortisol levels balanced

Gene set enrichment analysis (GSEA) was performed using the fgsea package, FA metabolism-related pathway enrichment was analyzed via the GSVA package, and Gene Ontology (GO) analysis was conducted with the clusterProfiler package

Ethical approval The RECOLAR study was conducted according to the guidelines of the Declaration of Helsinki, and approved by the Ethics Committee of the VU University Medical Center (RECOLAR: protocol code DC2019RECOLAR01, date of approval 16 September, 2020)

Nox4 participates in the chronic progression of PD through the synergistic effect of intranuclear ROS generation and -syn pathological toxicity (103)