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Barde, Swapnali

108 The increase in DKK1 in patients was related to the DKK1-mediated inflammation loop

With in-depth research on senkyunolides, particularly advances in clinical trials and the application of novel formulation technologies, this important active component is expected to become a valuable addition to the field of migraine treatment, bringing new hope to patients worldwide

All references to potential effects are for informational and educational purposes only

* Correspondence: Eva Liebau, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Iron-dependent ALOX enzymes can generate ROS to catalyze the oxidation of polyunsaturated fatty acids (PUFAs) ( 2+ is released in the cell by degradation, which promotes ferroptosis (Hou et al., 2016)