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Acknowledgments Special thanks to the Guelph Research and Development Centre and Agriculture and Agri-Food Canada for providing the financial support and allocated resources for this project

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Furthermore, most studies enrolled obese participants and were not specifically designed to evaluate menstrual patterns, which might cause bias

and speaker fees for Alexion, Astra-Zeneca, Bayer, Boehringer Ingelheim, GSK, Janssen, Medtronic, Novartis, and Otsuka