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A genome-wide association study demonstrated that the serine/threonine kinase encoding - ATM gene (ataxia telangiectasia mutated) has potential involvement in the mechanism of enzymes responsible for response to metformin (Figure 2

Gudenkauf, B., Goetsch, M

[DOI] [PMC free article] [PubMed] [Google Scholar] 72.Fink J.M., Hetzenecker A., Seifert G., Runkel M., Laessle C., Fichtner-Feigl S., Marjanovic G

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These DDSs may be customized to target drugs to the intended site of action precisely enhancing their half-life [1]