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In Crohns disease, malnutrition is present in up to 85% of patients, with active small intestinal involvement causing significant absorptive mucosal damage and blind loops resulting in bacterial overgrowth

Administration of the peptides also resulted in reduced development of free oxygen radicals causing oxidative destruction of lipids and proteins [3]

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doi: 10.1038/nm.3145 35 KristofferB.SkoogI.GustafsonD

Moreover, APAP-induced mitochondrial damage has been shown to partly result from the suppression of PPAR-regulated pathways, leading to irreversible inhibition of fatty acid oxidation

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