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[1] Commonly prescribed GLP-1 agonists include semaglutide (Ozempic for diabetes, Wegovy for weight management), dulaglutide (Trulicity), liraglutide (Victoza for diabetes, Saxenda for weight management), and exenatide (Byetta, Bydureon)

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10.1172/JCI78361 8 BravoJ

Metabolites are the ultimate products of metabolism and subsequently have the most direct bond to phenotype, providing readable information into the biochemical state of an organism and into perturbations in response to pathological conditions [21]

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Clinical trials showed reductions in triglycerides, LDL cholesterol, and increases in HDL cholesterol among patients taking semaglutide for weight management