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* Correspondence: Suman Adhikari, [email protected]

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Most of the cases of ALS are sporadic (sALS) with no genetic linkage, while around 10% are associated with familial forms (fALS), presenting mutations in over 20 genes

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However, approximately 1%2% of oxygen undergoes incomplete reduction, especially at complexes I and III, leading to electron leakage and superoxide generation

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Methanethiol (CH 3 SH, methyl mercaptan), ethanethiol (C 2 H 5 SH, ethyl mercaptan), propanethiol (C 3 H 7 SH), butanethiols (C 4 H 9 SH, n -butyl mercaptan and tert -Butyl mercaptan, are common reagents

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