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Despite these limitations, the level of evidence was classified as RCT, and the recommendation scope as General recommendation because the benefits significantly outweigh the risks

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Oral administration of nicotinamide mononucleotide is safe and efficiently increases blood nicotinamide adenine dinucleotide levels in healthy subjects

Understanding the optimal dosage, timing, and potential side effects of zinc supplementation or chelation will be crucial for the successful translation of these approaches into clinical practice