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Study monitoring Independent oversight committees included the Data Monitoring Committee (DMC), the Trial Steering Committee (TSC) and the Trial Management Committee, and were held on a regular basis throughout the trial

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In addition, whether GSH deficiency is the prime mode of the pro-oxidant actions of the GCL/GSS/glutamyl-amino acid transporter inhibitor, L-buthionine sulfoximine 4 needs to be revisited

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