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This comprehensive approach addresses metabolic dysfunction at multiple levels

doi: 10.1016/j.appet.2025.108139 127

This dual approach delivers the peptide both systemically and directly to follicles, addressing hair loss from multiple directions simultaneously

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and Akkermansia muciniphila , which correlated to reduced body weight and caloric intake following liraglutide and GUB09-145 treatment

Downregulating the expression of miR-23a and increasing the expression of the mitochondrial protective gene peroxisome proliferators-activated receptor- coactivator-1 (PGC-1) can exert an anti-apoptotic effect on human hepatocytes [34]