glp-1 pharmacology actions and target organs. GLP-1, through its receptor GLP-1R, Mechanisms of Action and Therapeutic

FIGURE 1 Octreotide-LAR Octreotide long-acting release (octreotide-LAR) is a somatostatin analogue that lowers the annual slope of TKV increase with no effect on renal function worsening

References: Altamimi, M., et al

Common gastrointestinal effects (affecting more than 1 in 10 people) include nausea, diarrhoea, and vomiting, particularly during the initial weeks of treatment or following dose increases

This distributes protein evenly, prevents blood sugar crashes, and avoids overwhelming a stomach that empties 30-40% slower than normal

In many cases, these early symptoms may signal the onset of more serious conditions that can lead to permanent vision loss if left undiagnosed

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