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GLP-1 related hair loss appears to be connected to rapid weight loss itself rather than a direct drug effect, a phenomenon called telogen effluvium that can occur with any rapid weight change

J Virol 99(3):e0217624 Yang J, Li Z, Ma R, Xie S, Wang D, Quan R, Liu J, Song J (2025) Seneca Valley virus 3 C protease targets TRIM32 for cleavage to antagonize its antiviral effects

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He clarifies that you lose both fat and some lean muscle, and essentially, the support system under the skin deflates