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Regular monitoring of renal function is advisable

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These work locally by drawing water into the rectum and lubricating stool

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Tirzepatide combines GLP-1 and GIP receptor agonists, targeting two hormone pathways involved in appetite regulation and metabolic control

It's worth noting that when GLP-1 receptor agonists are used alongside insulin or sulfonylureas, there is an increased risk of hypoglycaemia, and dose adjustments of these medications may be required