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A first search in the three scientific databases revealed 8830 published articles until 5 February 2024

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3.3.3 Activation of Nrf2 signaling pathway Polyphenols stimulate the activation of nuclear factor erythroid 2-related factor 2 (Nrf2), which in turn increases the production of detoxifying enzymes and proteins that play a role in the cellular antioxidant response (Laddha et al., 2024)