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Some doctors and health organizations have urged caution when prescribing weight loss drugs to adolescents due to potential mental health risks

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JANUVIA Tablets contain sitagliptin phosphate, an orally-active inhibitor of the dipeptidyl peptidase-4 (DPP-4) enzyme

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However, patients taking CNS depressants, opioids, or other sleep medications should discuss potential interactions with their physician before starting DSIP therapy