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doi:10.1182/blood-2008-03-040253

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Additionally, B-CQDs administered intravenously localised in kidneys and lymph nodes, intraperitoneally in intestines, liver, heart, and spinal cord, and orally in liver, kidneys, and lymphatic tissue, with peak tissue accumulation occurring at 30 min, and rapid systemic clearance within 2 hours [159]

The following formula was used to calculate the effective annualized sample size: The expected annual numbers of events in the intervention and placebo groups were estimated to be 147 and 177, respectively

Mean (SE) increases in serum creatinine were observed in patients treated with JANUVIA [0.12 mg/dL (0.04)] and in patients treated with placebo [0.07 mg/dL (0.07)]