These nutrients can be obtained through food, beverages, or supplements
Resistance of young rat hepatic mitochondria to bile acid-induced permeability transition: potential role of alpha-tocopherol
Exp Mol Med (2016) 48(3):e221
These findings render NNMT an attractive target in developing oligonucleotide drugs to prevent or treat obesity and T2D
Indeed, loss of glutathione peroxidase 4, a oxidation-resistant selenoprotein that utilizes GSH, leads to lipid peroxidation and subsequent ferroptosis, which is also found in epilepsy models ( The NADPH oxidase (NOX) family of enzymes is another relevant major source of ROS in the context of epilepsy as evidenced by activation of NOX2 by kainate-induced SE (Patel et al., 2005)
NTS, 164 a major critical knot for afferent signals of gastro-intestine and satiety