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In signaling studies using cell lines expressing GIPR or GLP-1R, tirzepatide demonstrated similar potency to GIP in activating GIPR (EC50 = 22.4 pM for tirzepatide vs

[DOI] [PMC free article] [PubMed] [Google Scholar] 84.Park J., Oh A.R., Lee S.H., et al

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Clinical trials of tirzepatide extended up to 72 weeks, with continued weight loss throughout the study period

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