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Diabetes and Cancer: Cancer Should Be Screened in Routine Diabetes Assessment

In standard functional assays, orforglipron shows greater than 100-fold selectivity for the GLP-1 receptor over the glucagon receptor, the GIP receptor, and the secretin receptor

GLP-1 medications are primarily used to treat type 2 diabetes and to support weight management

The search terms used were glucagon-like peptide 1 receptor agonist, exenatide, liraglutide, dulaglutide, lixisenatide, semaglutide, albiglutide, taspoglutide, loxenatide, diabetes mellitus, obesity and randomized controlled trial

Patients who used Zepbound for 36 weeks lost an average of 21%, but then, when switched to a placebo, after 1 year, they had regained 14% of their weight back

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