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As fat tissue grows and more NNMT is produced, higher amounts of hormones and pro-inflammatory signals are produced that are responsible for weight gain and other chronic diseases such as type 2 diabetes and cardiovascular disease. NNMT is responsible for converting nicotinamide (NA) into 1-methylnicotinamide (1-MNA), which takes it out of the NAD salvage pathway (see the diagram below)

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Why it matters Heavy metals accumulate in biological tissue and produce confounding effects in long-term studies

According to Dr Aravinda, high doses of vitamin B12 used to treat deficiency can cause: Headache Nausea and vomiting Diarrhoea Fatigue or weakness Tingling sensation in hands and feet Dr Aravinda further commented that possible interactions with other drugs include Aminosalicylic acid

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3 Receive assessment with a Registered Nurse, including vital signs and treatment suitability analysis