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The attenuated weight gain in both male and female PAR2-G37I mice, but not PAR2-R38E mice, was associated with significantly reduced hyperinsulinemia in fasted mice (Figure 3C)
Clinical trials showed significant weight loss: Average of 15-20% body weight with many losing more
Special considerations for compounded GLP-1 formulations Many people taking GLP-1 medications use compounded formulations rather than brand-name products
May provide additional metabolic benefits, including improved beta-cell function, reduced glucagon secretion, delayed gastric emptying, and increased satiety 22
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