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Mitochondrial Respiration in Blood Platelets of Depressive Patients

Its main function is to transport long-chain fatty acids (LCFA) from the cytoplasm to the mitochondrial matrix through the carnitine shuttle system, thereby entering the -oxidation process

In the second step, the thiol group of a cytosolic coenzyme A attacks the acyl-adenylate, displacing AMP to form thioester fatty acyl-CoA

PMC 4223629

Furthermore, the donated acetyl group from ALCAR serves a critical secondary purpose: it is the rate-limiting precursor for the synthesis of acetylcholine