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The decrease of mitochondrial oxidative phosphorylation in aging may contribute to the increase in the production of ROS

Additional studies that incorporate parameters such as buffer type, surfactants, salt concentration, pH and other excipients should be evaluated for their impact on the proposed detection mechanism

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14 , a041247 (2022)

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This oxidative stress damages mitochondrial components, including lipids, proteins, and mitochondrial DNA (mtDNA) [177]