Patients should consult their healthcare provider before adding berberine to their regimen and implement more frequent blood glucose monitoring if using both therapies
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As versatile therapeutic agents, GLP-1RAs demonstrated their benefits across a range of pain syndromes, including inflammatory nociception, visceral hypersensitivity, neuropathic pain, diabetic peripheral neuropathy (DPN), cancer pain and headaches (Fig
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Moreover, whereas existing formulations have enhanced convenience via weekly dosing and oral preparations, there is potential for innovation in delivery methods to increase patient adherence and comfort