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Example-3: Preparation- 1: Process for the preparation of Boc-His(Trt)-Aib-Glu(OtBu)-Gly-Thr(tBu)- Phe-Thr(tBu)-Ser(tBu)-Asp(OtBu)-Val-Ser(Oxa)-OH (fragment-7) Step-A: CTC resin (20 grams) was taken in a SPPS reactor and dichloromethane (120 mL) was added and allowed it to swell for 10 minutes

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OSA is characterized by recurrent upper airway collapse during sleep, leading to cyclical hypoxemia, hypercapnia, and sleep fragmentation

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