It works by stimulating insulin release (insulin secretion) when blood sugar levels are elevated, reducing glucagon secretion from the pancreas, and slowing gastric emptying to reduce appetite and enhance feelings of fullness
ENaC is thought to be the main receptor for the detection of NaCl or the taste salty [46]
GLP-1RAs, as an important class of drugs for the treatment of T2DM, shows significant advantages in blood glucose control, weight loss, cardiovascular protection and kidney benefit (Ussher and Drucker, 2023
Separately, another study suggested that longer durations of GLP-1RA treatment may help sustain weight loss even after discontinuation, although this hypothesis remains to be validated
Good instinct
However, the use of these medications is controversial because they are not approved by the U.S