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For tendon and joint injuries, injecting near the site outperforms systemic delivery

Molecules , 2020 This may be beneficial for individuals with spinal nerve impingements, post-surgical nerve damage, or even post-concussion inflammation

(Nature, 2014) used an antisense oligonucleotide to knock down NNMT in mice and reported reduced fat-mass gain, better glucose tolerance, and lower liver triglycerides the founding paper for the whole NNMT-inhibitor field

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