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The liver depends on intracellular glutathione for detoxification and that requires the compound to actually reach liver cells intact

These studies used the resources of the Augusta University Proteomics and Mass Spectrometry Core at Georgia Cancer Center

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doi: 10.2337/diacare.28.8.2042 140 Escobar-MorrealeHFLuque-RamirezM

There is a correlation between lower glutathione levels and IBS, impairing intestinal glutathione synthesis

So, you could end up with too much iron in your blood if you take the pill and supplements containing iron at the same time