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People with hypertension take blood pressure medication indefinitely

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Species can differ substantially in absorption, transport, hepatic metabolism, renal handling and off-target effects

PMID: 20 GilbertMPPratleyRE

In each level of all the subgroup variables, SGLT2i users reported significantly lower incidence of proliferative DR and composite surgical outcome than GLP1 users (Supplementary Tables 5 and 6)

The GLPs share the same underlying mechanism of action, but they differ in terms of formulations, administration, injection devices and dosages