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Among metabolic detoxification enzymes, GST is a family of multifunctional enzymes that are ubiquitously present in eukaryotes and prokaryotes, playing an important role in the detoxification of numerous endogenous and exogenous compounds

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Previous observations also highlighted the stimulatory role of IGF-2 in the proliferation [18] and expression of progesterone and estradiol in luteinized granulosa cells in humans [19, 20]

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