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The Sheehan Disability Scale, the Neuropathic Pain Symptom Inventory, and the Brief Pain Inventory were also used to evaluate the effects of the therapy on quality of life and the results demonstrated notable improvements

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Patients with type 2 diabetes and depressive symptoms received chronic candesartan administration for at least three months, which significantly improved interpersonal sensitivity and depression ratings and reset the HPA axis by reducing the sensitivity of the adrenals to ACTH and expression of AT1R (148)

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