Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3- methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl] thiazolidine): A highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
References: EMC SmPC: Basaglar (Sections 4.2 Posology and method of administration, 6.6 Special precautions for disposal)
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van der Ark KCH, Aalvink S, Suarez-Diez M, Schaap PJ, de Vos WM, Belzer C
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Another potential risk of relevance to older individuals is bone loss, which was observed with semaglutide (118), although combined treatment with an exercise program may potentially mitigate this risk (119)