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Weekly dose for both drugs can be increased to the next dose, every four weeks, or until the user shows better tolerability to the dose

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But if the timing coincides with a vial approaching its BUD, or if you suspect storage conditions were compromised, potency loss should be high on your list of possibilities

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It appears to be a direct pharmacological effect on neuroinflammation

Medical monitoring and investigations: Baseline liver function tests (LFTs) mandatory for agomelatine