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How do they complement each other

Limitations of the study The findings of this study could be considered with a few limitations

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As a result, the most noticeable changes often occur after you reach your maintenance dose

The p53(3KR) mutant, lacking acetylation due to lysine-to-arginine substitutions at three residues, decreases expression of SLC7A11 without affecting other p53 targets such as CDKN1A/p21 (involved in cell cycle progression) or BAX (involved in apoptosis)