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Shen Z, Lu P, Jin W, et al

2019 Jul 20;11(7)

This decline accelerates oxidative stress, inflammation, and disease risk [2]

Endocrinology and metabolism clinics of North America

In addition to these conventional sites of mitochondrial ROS generation, it has been recently reported that the branched-chain 2-oxoacid dehydrogenase (BCKDH) complex in mitochondria can produce superoxide and H 2 O 2 at higher rates than complex I from mitochondria (Quinlan et al., 2014)