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When the researchers blocked ferroptosis in aged mice, both oocyte number and quality improved ( Hu et al., FASEB Journal , 2025 )

They were often prescribed off-label by physicians in regenerative and longevity practices

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413 Partial ablation of astrocytes in the prefrontal cortex of healthy rats (by injection of gliotoxin L--aminoadipic acid) resulted in the development of depressive-like behaviours, whereas injection of neurotoxin ibotenate did not have such an effect