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Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality
Timing: Any time of day works
Underdosing means wasting time and product without results
Mild APAP-induced stress and consequent nuclear DNA damage can also activate the DNA damage response (DDR) pathway 33,34,35 , cell cycle arrest 36 , and can trigger senescence 14,35
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