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(2) the specific CI inhibitor IACS-010759 was recently reported to promote neurotoxicity, making this an unattractive agent for combination therapy in CRC given the neurotoxicity long-recognized with oxaliplatin treatment 51

To support the growth of good bacteria and re-establish balance in the microbiome, incorporate plenty of prebiotic and probiotic foods: root vegetables, kimchi and other fermented foods, yogurt, kefir, and kombucha

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These medications may indirectly improve insulin sensitivity through weight loss and improved glycaemic control