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But the same disruption means the skin is more reactive to potential irritants in the formulation, including preservatives, fragrances, surfactants, and even some peptide stabilizers

It actively increases how many calories your body burns, even at rest

It is particularly great for people who experience constipation, irregular digestion, or whose diet is low-fiber

Additionally, apremilasts efficacy extends beyond plaque psoriasis to difficult-to-treat cases such as palmoplantar and scalp psoriasis, where significant symptom improvement has been documented (Rich et al

doi: 10.1016/j.amjmed.2014.04.017 144 AzzizRCarminaEChenZDunaifALavenJSLegroRSet al