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Previous solution-phase studies and computational models of GLP-1 and exendin-4 indicated that the N-terminal had a type II beta turn, but more recent results concluded that the secondary structure of peptides, when bound to class B GPCRs of which the GLP-1R is one, is helical all through the sequence (41)

doi: 10.1053/j.gastro.2011.10.001 12 KaplanGGWindsorJW

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Epithelial ovarian cancer: evolution of management in the era of precision medicine