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What to Expect When Switching: First 2-4 Weeks: Side effects may recur even if you tolerated the first medication well Nausea and GI symptoms are common during transition Appetite changes may feel different Weight loss may slow temporarily Weeks 4-12: Body adjusts to new medication Side effects typically improve Appetite suppression becomes consistent Weight loss resumes or accelerates (especially switching to tirzepatide) After 3 Months: Full effects of new medication apparent Can assess if switch was beneficial May adjust dose based on results and tolerance Switching Success Rates: Most patients successfully transition between medications

Substance P is an important neuropeptide and acts as both a vasodilator and sympathetic activator

Looking at the big picture helps you push through

Patients must also budget for follow-up appointments with their prescribing provider, which may occur every 4 weeks during dose escalation

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