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Coronary microvascular dysfunction: evolving understanding of pathophysiology, clinical implications, and potential therapeutics

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People with Hutchinson-Gilford progeria syndrome experience severe hardening of the arteries (arteriosclerosis) beginning in childhood

Both muscarinic receptors and GLP-1Rs are GPCRs, but they function in different physiological contexts: muscarinic receptors are primarily involved in the ANS, while GLP-1Rs play a key role in metabolic control