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Unlike traditional GLP-1 medications that activate a single hormone pathway, tirzepatide works by targeting two important metabolic hormones: Glucose-dependent insulinotropic polypeptide (GIP) Glucagon-like peptide-1 (GLP-1) These hormones play a role in: Appetite control Hunger signaling Blood sugar regulation Insulin production Energy utilization Metabolic function By activating both pathways, tirzepatide helps support a more comprehensive metabolic response than medications that target GLP-1 receptors alone