The slowed gastric emptying from GLP-1 therapy could theoretically exacerbate inflammation or obstruction risk in active Crohn's, though controlled clinical data specific to this population remains limited
This warning applies to all medications containing semaglutide, including Wegovy, as well as other GLP-1 agonists like Ozempic and Rybelsus, which are used for Type 2 diabetes (and off-label for weight loss)
The EMA concluded that the benefits of Ozempic, as evidenced in clinical trials, outweighed the potential risks, leading to its approval for use in the European Union
The one place I see more scrutiny is with extended-release versions, which sometimes require extra steps for approval. Prior authorization Per Dr
**Dependence**: Overuse of any drug can potentially lead to psychological dependence
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