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This creates a self-reinforcing cycle: low testosterone promotes further fat accumulation, which drives more aromatase conversion, leading to even lower testosterone (Cohen, 1999, Journal of Clinical Endocrinology & Metabolism )
Altered levels of AMPK and inhibition of AMPK activity induce maturation defects in mouse oocytes, which severely impact oocyte quality [99]
Verma, A.K., Catassi, C
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